Canned motor pump for lyophilisation / freeze-drying

Freeze-drying, also known as lyophilisation, is used in various branches such as pharmaceutics or the food industry to prolong the product life. Hereby the product is cooled down to a temperature between –50 °C and –90 °C in industrial freeze-dryers so that the water in the product is turned into ice. The chamber will be vacuumized afterwards, so that the frozen water evaporates without adopting a liquid aggregate state. The water vapour is separated at an ice condenser which is also heavily cooled. Finally, the product is heated up to remove residual moisture. To do this, a constant, precise temperature control is required both for freezing and for condensing the water vapour. In the primary circuit, a synthetic refrigerant cools the secondary circuit which circulates a silicone oil by means of a pump to cool shelves and the condenser.

Your benefits

  • Material: Material resistance to low temperatures up to –90 °C 
  • Safety: Absolute leak-tightness of the system even when using coolants with high requirements
  • Energy efficiency: Lowest life cycle costs thanks to low maintenance costs

Application areas

  • Pharmaceutics industry 
  • Food industry 
  • Preservation industry

Industrial freeze-dryers in medicine production

Requirements

In this application, the requirement was to select a suitable pump for the secondary circuit of an industrial refrigeration chamber in the field of medicine production. The application temperature range required was –60 °C to +80 °C. The long service life and no-maintenance requirement were also important. The servicing intervals for the pump should be as long as possible.

Delivery rate:42 m3/h
Pumping head:15 m
Operating temperature: –60 °C bis +80 °C
Refrigerant: Silikonöl KT3
Material:Edelstahl

The pump used

The pump is made from stainless steel due to the low operating temperatures. A CNF50-160 with AGX6.5 motor was used. This is a single-stage canned motor pump with a pressure rating of PN25. This single-stage pump series is particularly suitable for high delivery rates and medium pumping heads. The customer was also particularly impressed by the long, maintenance-free service life and HERMETC’s experience in the handling of low temperatures.

Medium / refrigerant

Silicone oils are used as refrigerants especially in the low temperature range. Baysilone KT3, for example, features a low solidification point of < –100 °C, a high thermal stability and low vapour pressures. In addition, the silicone oil is non-corrosive. Silicone oils, however, are very expensive in comparison with other refrigerants. Everything you need to know about silicone oils is available here.

We have the right pumps for your industry

CAM stainless steel

Delivery rate:max. 45 m3/h
Pumping head:max. 190 m
Pressure rating:PN 25
Operating temperature: –90 °C to +30 °C
Motor: AGX 1.0 – AGX 6.5
Material:Stainless steel 1.4571

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CNF stainless steel

Delivery rate:max. 85 m3/h
Pumping head:max. 90 m
Pressure rating:PN1 6 / PN 25
Operating temperature: –90 °C to +30 °C
Motor:AGX 3.0 – CKPx 19.0
Material:Stainless steel 1.4408

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Customisation

If you cannot find a suitable pump series? We are happy to help you with a customised solution regardless of the quantity. Please contact us for further information.

Download application report

Application Report 

Lyophilisation / Freeze-drying

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Your contact person

For more information, please contact:

Adrian Schaefer

Product Manager